Stem Cell Niches for Skin Regeneration

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Stem Cell Niches for Skin Regeneration

Stem cell-based therapies offer tremendous potential for skin regeneration following injury and disease. Functional stem cell units have been described throughout all layers of human skin and the collective physical and chemical microenvironmental cues that enable this regenerative potential are known as the stem cell niche. Stem cells in the hair follicle bulge, interfollicular epidermis, derm...

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Stem/Progenitor Cell Niches Involved in Hepatic and Biliary Regeneration

Niches containing stem/progenitor cells are present in different anatomical locations along the human biliary tree and within liver acini. The most primitive stem/progenitors, biliary tree stem/progenitor cells (BTSCs), reside within peribiliary glands located throughout large extrahepatic and intrahepatic bile ducts. BTSCs are multipotent and can differentiate towards hepatic and pancreatic ce...

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Plant stem cell niches.

Stem cells are required to support the indeterminate growth style of plants. Meristems are a plants stem cell niches that foster stem cell survival and the production of descendants destined for differentiation. In shoot meristems, stem cell fate is decided at the populational level. The size of the stem cell domain at the meristem tip depends on signals that are exchanged with cells of the org...

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Artificial stem cell niches.

Stem cells are characterized by their dual ability to reproduce themselves (self-renew) and specialize (differentiate), yielding a plethora of daughter cells that maintain and regenerate tissues. In contrast to their embryonic counterparts, adult stem cells retain their unique functions only if they are in intimate contact with an instructive microenvironment, termed stem cell niche. In these n...

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Germline stem cell niches

1. The anatomically simplest GSC niche in C. elegans . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 2. The first structurally and functionally defined GSC niche in the Drosophila ovary . . . . . . . . . . . . . . . . . . . . 4 3. The structurally and mechanistically well-studied GSC niche in the Drosophila testis . . . . . . . . . . . . . . . . . 6 4...

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ژورنال

عنوان ژورنال: International Journal of Biomaterials

سال: 2012

ISSN: 1687-8787,1687-8795

DOI: 10.1155/2012/926059